The effect of enzymatic hydrolysis of raspberry solid wastes on phenolic antioxidant extraction process was studied. Proximal composition of raspberry wastes was determined; this by-product presented high content of crude fiber (60%) and low values of protein, oil and ash. Biocatalysts which contain a combination of cellulase, hemicellulase and pectinase activities would be useful for carrying out an enzymatically assisted antioxidant extraction based on the fiber composition of these residues. Hydroalcoholic extraction was carried out using different commercial enzymes. Total phenol content and antioxidant activity of enzyme-hydrolyzed extracts were measured and compared with those obtained without enzyme application. All biocatalyst evaluated increased soluble solids in comparison to the non-enzymatic controls. Among them, Grindamyl and Maxoliva offered the best recovery of polyphenols. Enzymatic assisted extraction with an hydro-ethanolic mixture (75 : 25, v/v) during 18 hrs at 50°C enhanced the phenolic content up to 35% and the antioxidant capacity around 50%, 15% and 30% according to DPPH, ABTS and FRAP methods, respectively. Use of higher enzyme concentration significantly improved the phenolic antioxidants extraction.